The symptoms of Mesothelioma (a form of cancer) can take between 20 and 50 years to develop. Unfortunately, this delay can prevent the discovery of the disease and result in wrong diagnoses. The beginning signs are like many other illnesses, such as colds or the flu, and, as a result, can be rejected . Another quality of mesothelioma is respiratory problems, such as pain in the chest and difficulty breathing. The three forms of mesothelioma each have a little bit different symptoms.